Lipids & metabolic liver disease
Triglyceride-glucose index is associated with myocardial ischemia and poor prognosis in patients with ischemia and no obstructive coronary artery disease
Main finding · Abnormal MPI (myocardial ischemia)Result — go to the resultOdds ratio 1.901 95% CI 1.045–3.458Authors' conclusion
This study indicates for the first time that the TyG index is significantly associated with myocardial ischemia and poor prognosis among INOCA patients.
Study context
- Population
- INOCA patients who underwent both coronary angiography and myocardial perfusion imaging (MPI)
- Participants
- 332 patients
- Exposure
- Triglyceride-glucose (TyG) index tertiles
- Outcome
- Myocardial ischemia (abnormal MPI: Summed stress score (SSS) ≥ 4 and summed difference score (SDS) ≥ 2) and MACE
Methodological detailsconsecutive enrolment
- Consecutive enrolment
Main finding
Abnormal MPI (myocardial ischemia)
Odds ratio
1.901
95% CI 1.045–3.458
P = 0.035
High TyG index
OR 1.901 (95% CI 1.045–3.458); P = 0.035
As reported in the abstract
- Abnormal MPI, all INOCA patients
- 113 (34.0%)
Observational data: associations, not effects.
Further findings
MACE · median 35 months of follow-up — T3 vs T2 · across tertiles (T3 vs T2 vs T1)
P = 0.001
| Outcome | HR (95% CI) | P value | |
|---|---|---|---|
| MACE · median 35 months of follow-upT3vs T1Multivariate Cox regression | 2.338 (1.253–4.364) | P = 0.008 | |
| 0.20.5125Hazard ratio (log scale) |
- Major adverse cardiac events (MACE) — MACE recorded, all patients
- 83 (25%)
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Triglyceride-glucose index is associated with myocardial ischemia and poor prognosis in patients with ischemia and no obstructive coronary artery disease. Cardiovasc Diabetol. Published 31 May 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →