Lipids & metabolic liver disease
Correlation between the triglyceride-glucose index and left ventricular global longitudinal strain in patients with chronic heart failure: a cross-sectional study
Authors' conclusion
Elevated TyG index may be independently associated with more severe clinical left ventricular dysfunction in patients with CHF.
Study context
- Population
- Patients with chronic heart failure (HF) (chronic heart failure (CHF))
- Participants
- 427 patients
- Exposure
- Higher vs lower triglyceride-glucose (TyG) index
- Outcome
- Left ventricular GLS
Methodological detailsTyG index = Ln [fasting triglyceride (TG) (mg/dL) × fasting plasma glucose (FPG) (mg/dL)/2]
- TyG index = Ln [fasting TG (mg/dL) × FPG (mg/dL)/2]
Main finding
As reported in the abstract
- Global longitudinal strain (GLS) notably lower in the higher vs lower TyG index group
- After adjustment for confounders, GLS decreased gradually with increasing TyG index, regardless of left ventricular ejection fraction (LVEF) level and CHF classification
Observational data: associations, not effects.
Original publication
Correlation between the triglyceride-glucose index and left ventricular global longitudinal strain in patients with chronic heart failure: a cross-sectional study. Cardiovasc Diabetol. Published 29 May 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →