Thyrotoxic periodic paralysis - a retrospective study from Southern India
Authors' conclusion
This is one of the largest series of thyrotoxic periodic paralysis cases in India. In subjects with thyrotoxicosis, serum potassium, free T4, total T4 and total T3 levels were significantly lower in those with periodic paralysis than in those without.
Study context
- Population
- Patients with thyrotoxicosis at a tertiary care centre in southern Indiacases and controls
- Participants
- 41 patients
- Comparison
- Thyrotoxicosis with periodic paralysis (cases) vs thyrotoxicosis without paralysis (controls)
- Outcome
- Clinical and biochemical features
Methodological detailssingle tertiary care centre, consecutively selected controls
- Single tertiary care centre
- Consecutively selected controls
Main finding
As reported in the abstract
- Mean serum potassium, FT4, total T4 and total T3 significantly lower in cases than controls
Observational data: associations, not effects.
Further findings
Male sex
GD as aetiology of thyrotoxicosis · most common aetiology in both groups
Goitre
Age
- Presentation without clinical thyrotoxic features (cases)
- 20%
Goitre
- Prevalence significantly higher among controls
Additional aetiology for persistent hypokalaemia (cases)
- Patients with likely Gitelman's syndrome
- 2
Original publication
Thyrotoxic periodic paralysis - a retrospective study from Southern India. Eur Thyroid J. Published 11 November 2024. doi:10.
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