The Impact of Baseline Sleep as a Potential Moderator of Weight Loss Intervention in Breast Cancer Survivors: Results From the POWER ‐Remote Trial
Authors' conclusion
BWL has greater effects in breast cancer survivors with better versus worse sleep. Studies should evaluate whether sleep disturbance treatment augments weight loss.
Study context
- Population
- Women with prior stage 0-III breast cancer with BMI ≥ 25 kg/m²
- Participants
- 47 vs 46
- Comparison
- Behavioral weight loss vs self-directed approach, by baseline sleep
- Behavioral weight loss (BWL)n = 47
- Self-directedn = 46reference
- Primary endpoint
- Weight loss, moderated by baseline sleep disturbance (NIH PROMIS Adult Sleep Disturbance Short Form)
- Follow-up
- 6 and 12 months
Methodological detailsmoderator analysis, stratified by baseline sleep
- Moderator analysis
- Stratified by baseline sleep
Primary result
As reported in the abstract
Weight loss by baseline sleep (BWL vs self-directed)
- 6 months; SE 1.42%
- weight loss difference, better sleepers −6.16 %; P < 0.001
- 12 months; SE 2.02%
- weight loss difference, better sleepers −7.53 %; P = 0.001
- 6 months; SE: 1.58%
- weight loss difference, poor sleepers −3.15 %; P = 0.056
- 12 months; SE: 2.40%
- weight loss difference, poor sleepers −2.44 %; P = 0.321
Original publication
The Impact of Baseline Sleep as a Potential Moderator of Weight Loss Intervention in Breast Cancer Survivors: Results From the POWER ‐Remote Trial. Obesity (Silver Spring). Published 15 December 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →