Obesity

Comprehensive cognitive training improves anthropometric measures in people with excess weight: the TRAINEP randomized controlled trial

Int J Obes (Lond)Published Randomised controlled trial

Authors' conclusion

A comprehensive cognitive training delivered as an add-on to BWLI improved anthropometric outcomes in individuals with excess weight, with sustained effects over 6 months.

Study context

Population
Individuals with excess weight (126 women of 148; mean BMI 31.62 kg/m²)128 completed
Participants
148 individuals
Comparison
Comprehensive cognitive training + behavioral weight-loss intervention (BWLI) vs sham cognitive training + BWLI vs BWLI alone
Primary endpoint
Anthropometric measures: BMI, weight, %WL and waist-to-height ratio
Follow-up
Post-treatment, 3- and 6-month follow-ups
Methodological detailsthree-arm, sham-controlled
  • Three-arm
  • Sham-controlled

Primary result

As reported in the abstract

Anthropometric measures (group-by-time interaction) · post-treatment to 6-month follow-up
Group-by-time interaction, BMI
p = 0.009
Group-by-time interaction, weight
p = 0.003
Group-by-time interaction, %WL
p = 0.004
Group-by-time interaction, waist-to-height ratio
p = 0.041

Further findings

Higher proportion achieved clinically meaningful %WL with Cognitive

Original publication

Comprehensive cognitive training improves anthropometric measures in people with excess weight: the TRAINEP randomized controlled trial. Int J Obes (Lond). Published 8 January 2026. doi:10.1038/s41366-025-02012-z

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