Stroke Incidence Evolution in People With Newly Diagnosed Diabetes and Impaired Glucose Tolerance: A 34-Year Follow-up of the Da Qing Diabetes Study
Authors' conclusion
Over 34 years, ∼50% of Chinese adults with NDD and IGT experienced stroke. Further efforts in diabetes management and intervention are required.
Study context
- Population
- Chinese adults with NDD, impaired glucose tolerance (IGT) and normal glucose tolerance (NGT) identified in 1986 in the Da Qing Diabetes Prevention Study
- Exposure
- NDD vs IGT vs NGT
- Outcome
- Stroke incidence
- Follow-up
- 34 years
Methodological details34-year follow-up, IGT participants randomized to 6-year lifestyle intervention or control
- 34-year follow-up
- IGT participants randomized to 6-year lifestyle intervention or control
Main finding
As reported in the abstract
Stroke
Hazard ratio (95% CI)P value
NDDvs NGTadjusted for risk factors
1.80(1.46–2.21)
P < 0.001IGT noninterventionvs NGTadjusted for risk factors
1.52(1.11–2.07)
P = 0.008IGT interventionvs NGTadjusted for risk factors
1.33(1.17–1.63)
P = 0.01IGT interventionvs NDD
0.77(0.64–0.94)
P = 0.009Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | P value | |
|---|---|---|---|
| Stroke, women · 34 yearsIGT interventionvs NDD | 0.64 (0.47–0.88) | P = 0.006 | |
| 0.512Hazard ratio (log scale) |
Original publication
Stroke Incidence Evolution in People With Newly Diagnosed Diabetes and Impaired Glucose Tolerance: A 34-Year Follow-up of the Da Qing Diabetes Study. Diabetes Care. Published 15 May 2025. doi:10.
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