Cruciferous vegetables improve glycaemic control compared to root/squash vegetables in a randomized, controlled, crossover trial: The VEgetableS for vaScular hEaLth ( VESSEL ) study
Primary result · Glycaemic variability (CV)Result — go to the resultMean difference −2.0 % 95% CI −2.8 to −1.1Authors' conclusion
Cruciferous vegetable consumption improved postprandial glycaemic control compared with root/squash vegetables. The clinical impact remains uncertain and warrants further investigation, particularly in individuals with impaired glycaemic control.
Study context
- Population
- Non-diabetic adults with elevated blood pressure; median (IQR) age 68 (66–70) years, 89% female18 completed
- Comparison
- Cruciferous vegetables vs root/squash vegetables
- Primary endpoint
- Glycaemic control (glycaemic measures were a pre-specified secondary outcome of the trial), measured by flash glucose monitoring every 15 min
- Follow-up
- 2-week interventions
Methodological detailscrossover, participant-blinded, 2-week washout
- Crossover
- Participant-blinded
- 2-week washout
Primary result
Glycaemic variability (CV)
Mean difference
−2.0 %
95% CI −2.8 to −1.1
P < 0.001
Activevs Control
mean difference −2.0 % (95% CI −2.8 to −1.1); P < 0.001
As reported in the abstract
Secondary outcomes
| Outcome | Mean difference (mmol/L) (95% CI) | P value | |
|---|---|---|---|
| Overall PPGR 2-h (2-h mean glucose) | −0.14 (−0.24 to −0.04) | P = 0.005 | |
| −0.3−0.2−0.100.1Difference, mmol/L (linear scale) |
| Outcome | Mean difference (mmol/L × min) (95% CI) | P value | |
|---|---|---|---|
| Overall PPGR AUC | −20.1 (−34.1 to −6.1) | P = 0.005 | |
| −40−20020Difference, mmol/L × min (linear scale) |
| Outcome | P value |
|---|---|
| Dinner PPGR (2-h and AUC)Active vs Control · dinner PPGR 2-h | P = 0.004 |
| Dinner PPGR (2-h and AUC)Active vs Control · dinner PPGR AUC | P = 0.003 |
| Mean continuous glucose | P = 0.411 |
Dinner PPGR (2-h and AUC)
- Overall PPGR differences driven by the dinner PPGR
Mean continuous glucose
- No difference in mean continuous glucose for active vs control
Original publication
Cruciferous vegetables improve glycaemic control compared to root/squash vegetables in a randomized, controlled, crossover trial: The VEgetableS for vaScular hEaLth ( VESSEL ) study. Diabetes Obes Metab. Published 15 May 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →