Influence of a diet and/or exercise intervention on long‐term mortality and vascular complications in people with impaired glucose tolerance: Da Qing Diabetes Prevention Outcome study
Authors' conclusion
A diet-only intervention and a diet-plus-exercise intervention in people with IGT were significantly associated with a reduced risk of all-cause death, CVD death and CVD events, while an exercise-only intervention was not. It suggests that diet-related interventions may have a potentially more reliable influence on long-term vascular complications and mortality.
Study context
- Population
- People with impaired glucose tolerance (IGT), Da Qing Diabetes Prevention Study540 completed follow-up
- Participants
- 576 people
- Comparison
- Diet-only, exercise-only and diet-plus-exercise interventions vs control
- Primary endpoint
- Long-term all-cause mortality and cardiovascular disease (CVD) events (all-cause death, CVD death, CVD events)
- Follow-up
- Up to 24 years after end of 6-year intervention
Methodological detailsprospective cohort study, randomized lifestyle intervention, follow-up up to 24 years after 6-year intervention
- Prospective cohort study
- Randomized lifestyle intervention
- Follow-up up to 24 years after 6-year intervention
Primary result
As reported in the abstract
All-cause death, CVD death and CVD events
Each group vs controlEstimate (95% CI)
Diet-only
HR (all-cause death) 0.77(0.61–0.97)
Diet-only
HR (CVD death) 0.67(0.46–0.97)
Diet-only
HR (CVD events) 0.72(0.54–0.96)
Diet-plus-exercise
HR (all-cause death) 0.64(0.48–0.84)
Diet-plus-exercise
HR (CVD death) 0.54(0.30–0.97)
Diet-plus-exercise
HR (CVD events) 0.68(0.52–0.90)
Original publication
Influence of a diet and/or exercise intervention on long‐term mortality and vascular complications in people with impaired glucose tolerance: Da Qing Diabetes Prevention Outcome study. Diabetes Obes Metab. Published 2 January 2024. doi:10.
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