Effectiveness of an Incentives-Enhanced Stepped Care Intervention Program in Diabetes Prevention in a Multiethnic Asian Prediabetes Cohort: Results From the Pre-DICTED Randomized Controlled Trial
Authors' conclusion
A stepped care diabetes prevention program, enhanced with financial incentives, effectively reduced diabetes conversion in a multiethnic Asian prediabetes cohort.
Study context
- Population
- Overweight or obese individuals with impaired glucose tolerance, impaired fasting glucose, or both; multiethnic prediabetes cohort in Singapore
- Participants
- 751 participants
- Comparison
- Incentives-enhanced stepped care prevention program vs standard care
- Primary endpoint
- Proportion of participants developing diabetes, modified ITT population
- Follow-up
- 3 years
Primary result
As reported in the abstract
Developed diabetes
Adjusted risk difference, % (95% CI)P value
Interventionvs Control
−10.93(−18.04 to −3.81)
P = 0.003Adjusted relative risk (95% CI)P value
Interventionvs Control
0.74(0.62–0.88)
P < 0.001Further findings
Intervention uptake in the intervention arm
- Received metformin
- 26.4%
- Received cash incentives
- 45.1%
Safety
- Adverse events more common in the intervention arm, mainly metformin-related gastrointestinal symptoms
Original publication
Effectiveness of an Incentives-Enhanced Stepped Care Intervention Program in Diabetes Prevention in a Multiethnic Asian Prediabetes Cohort: Results From the Pre-DICTED Randomized Controlled Trial. Diabetes Care. Published 19 September 2025. doi:10.
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