Sleep‐disordered breathing and cardiometabolic and inflammatory markers in children with overweight/obesity: The role of cardiorespiratory fitness
Authors' conclusion
SDB severity was positively associated with CRP independently of the adiposity levels, but not with other inflammatory or cardiometabolic risk factors in children with overweight/obesity. Moreover, our results suggest that higher levels of cardiorespiratory fitness may attenuate the adverse effect of SDB severity on systematic inflammation in children with overweight/obesity.
Study context
- Population
- Children aged 8–11 years with overweight/obesity
- Participants
- 109 children
- Exposure
- Low cardiorespiratory fitness vs High cardiorespiratory fitness
- Outcome
- Association of SDB severity (reduced Paediatric Sleep Questionnaire) with cardiometabolic and inflammatory markers, independent of adiposity
Main finding
As reported in the abstract
Sleep-disordered breathing (SDB) severity positively related to CRP, β
0.352
p = 0.002
Observational data: associations, not effects.
Further findings
| Outcome | Low cardiorespiratory fitness | High cardiorespiratory fitness |
|---|---|---|
| SDB–CRP association stratified by cardiorespiratory fitness | ||
| β | 0.465 | 0.236 |
| p | p = 0.014 | p = 0.108 |
Interaction of cardiorespiratory fitness on SDB–CRP association
- Positive trend for interaction effect
- P = 0.1
Original publication
Sleep‐disordered breathing and cardiometabolic and inflammatory markers in children with overweight/obesity: The role of cardiorespiratory fitness. Pediatr Obes. Published 21 January 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →