Gestational diabetes & diabetes in pregnancy
Shortcut to the needle in the haystack? Screening for maturity onset diabetes of the young in a population of women with gestational diabetes
Authors' conclusion
The current Danish GDM screening guidelines do not apply with recommending the use of pre-pregnancy BMI <25 kg/m2 and fasting glucose ≥5.5 mmol/L as criteria for identifying women with GCK-MODY among women with GDM in the Danish population.
Study context
- Population
- Women diagnosed with GDM in the Central Denmark Region, April 2019–December 2022; screening offered to those with pre-pregnancy body mass index (BMI) <25 kg/m² and fasting glucose ≥5.5 mmol/L34 screened
- Participants
- 1,270 women
- Outcome
- Identification of GCK-MODY (and other MODY subtypes; 17 known genetic variants) among women with GDM meeting the combined criteria
Methodological detailssingle-region, genetic screening by Next Generation Sequencing
- Single-region
- Genetic screening by Next Generation Sequencing
Main finding
As reported in the abstract
MODY identified by screening
Met MODY screening criteria
46
Offered MODY screening
41
Participated in screening
34
Identified with MODY (MODY 8-CEL variant)
1
Observational data: associations, not effects.
Original publication
Shortcut to the needle in the haystack? Screening for maturity onset diabetes of the young in a population of women with gestational diabetes. Diabet Med. Published 7 March 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →