Gestational diabetes & diabetes in pregnancy
Comparing efficacy in glycaemic control and pregnancy outcomes between continuous glucose monitoring and self-monitoring of blood glucose in pregnancies complicated by gestational diabetes mellitus: a systematic review and meta-analysis
Authors' conclusion
These findings suggest CGM improves glycaemic control in GDM and reduces maternal and neonatal complications.
Study context
- Population
- Pregnancies complicated by gestational diabetes mellitus (GDM); studies published January 1980–April 2026 in PubMed, Embase, Scopus, Cochrane Library and Web of Science
- Participants
- 5,650 pregnant women21 studies
- Comparison
- Continuous glucose monitoring (CGM) vs self-monitored blood glucose (SMBG)
- Outcome
- Glycaemic control measures
Methodological detailspreregistered with PROSPERO, Risk of bias assessed using Jadad scale and Newcastle-Ottawa Scale; low-to-moderate bias risks
- Preregistered with PROSPERO
- Risk of bias assessed using Jadad scale and Newcastle-Ottawa Scale; low-to-moderate bias risks
Pooled result
As reported in the abstract
Glycaemic control
Each group vs SMBGEstimate (95% CI)
CGM
MD (mean blood glucose) −0.24 mmol/L(−0.41 to −0.06)
CGM
MD (mean amplitude of glycaemic excursions) −0.22 mmol/L(−0.43 to −0.02)
Each group vs SMBGEstimate (95% CI)
CGM
MD (CV) −0.78 %(−1.50 to −0.06)
CGM
MD (TAR > 7.8 mmol/L) −2.19 %(−3.78 to −0.60)
Further pooled results
Medication use
- CGM associated with increase in medication use
- 21%
Adverse maternal and neonatal outcomes (caesarean delivery, macrosomia, neonatal hypoglycaemia, hyperbilirubinemia)
- CGM associated with reduction in adverse maternal and neonatal outcomes
- 8-35%
Original publication
Comparing efficacy in glycaemic control and pregnancy outcomes between continuous glucose monitoring and self-monitoring of blood glucose in pregnancies complicated by gestational diabetes mellitus: a systematic review and meta-analysis. Diabetes Res Clin Pract. Published 13 August 2026. doi:10. 1016/ j. diabres. 2026. 113488
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