Gestational diabetes & diabetes in pregnancy

Comparing efficacy in glycaemic control and pregnancy outcomes between continuous glucose monitoring and self-monitoring of blood glucose in pregnancies complicated by gestational diabetes mellitus: a systematic review and meta-analysis

Diabetes Res Clin PractPublished Systematic review and meta-analysis of randomised controlled trials and observational studies

Authors' conclusion

These findings suggest CGM improves glycaemic control in GDM and reduces maternal and neonatal complications.

Study context

Population
Pregnancies complicated by gestational diabetes mellitus (GDM); studies published January 1980–April 2026 in PubMed, Embase, Scopus, Cochrane Library and Web of Science
Participants
5,650 pregnant women21 studies
Comparison
Continuous glucose monitoring (CGM) vs self-monitored blood glucose (SMBG)
Outcome
Glycaemic control measures
Methodological detailspreregistered with PROSPERO, Risk of bias assessed using Jadad scale and Newcastle-Ottawa Scale; low-to-moderate bias risks
  • Preregistered with PROSPERO
  • Risk of bias assessed using Jadad scale and Newcastle-Ottawa Scale; low-to-moderate bias risks

Pooled result

As reported in the abstract

Glycaemic control
Each group vs SMBGEstimate (95% CI)
CGM
MD (mean blood glucose) −0.24 mmol/L(−0.41 to −0.06)
CGM
MD (mean amplitude of glycaemic excursions) −0.22 mmol/L(−0.43 to −0.02)
Each group vs SMBGEstimate (95% CI)
CGM
MD (CV) −0.78 %(−1.50 to −0.06)
CGM
MD (TAR > 7.8 mmol/L) −2.19 %(−3.78 to −0.60)

Further pooled results

Medication use

CGM associated with increase in medication use
21%

Adverse maternal and neonatal outcomes (caesarean delivery, macrosomia, neonatal hypoglycaemia, hyperbilirubinemia)

CGM associated with reduction in adverse maternal and neonatal outcomes
8-35%

Original publication

Comparing efficacy in glycaemic control and pregnancy outcomes between continuous glucose monitoring and self-monitoring of blood glucose in pregnancies complicated by gestational diabetes mellitus: a systematic review and meta-analysis. Diabetes Res Clin Pract. Published 13 August 2026. doi:10.1016/j.diabres.2026.113488

Composed by AI from the published abstract and checked against it. How Briefs are made →

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