Gestational diabetes & diabetes in pregnancy

Type 2 Diabetes Risk After Gestational Diabetes According to Country/Region of Origin: A Nationwide Register-based Study

J Clin Endocrinol MetabPublished Nationwide register-based cohort study

Authors' conclusion

This study demonstrated that country/region of origin is an important risk factor for T2DM in women with GDM. These findings underscore the importance of prevention programs targeting women with GDM and a high-risk origin.

Study context

Population
Women diagnosed with gestational diabetes mellitus (GDM) in Denmark 2004–2018, followed to December 31, 202022.3% migrant, 77.7% Danish
Participants
20,873 women
Exposure
Migrant women by country/region of origin vs Danish women
Outcome
Incidence rates of T2D according to country/region of origin
Follow-up
Mean 7.3 years
Methodological detailsPoisson regression adjusted for age, education and BMI
  • Poisson regression adjusted for age, education and BMI

Main finding

As reported in the abstract

IRs of T2D

Women from Pakistan and Sri Lanka had higher incidence rates (IRs) vs Danish women

3 to 4 times

Observational data: associations, not effects.

Further findings

Overall T2D during study period · mean follow-up 7.3 years

Registered with T2D
10.9%

Timing of T2D onset

Earlier T2D onset in women from Sri Lanka and Pakistan vs other migrant and Danish women

Original publication

Type 2 Diabetes Risk After Gestational Diabetes According to Country/Region of Origin: A Nationwide Register-based Study. J Clin Endocrinol Metab. Published 1 March 2024. doi:10.1210/clinem/dgae113

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