Lipids & metabolic liver disease
Remnant cholesterol has a non-linear association with non-alcoholic fatty liver disease
Authors' conclusion
Elevated RC levels were found to be linked to NAFLD, even after controlling for traditional risk factors. Moreover, non-linear pattern in the relationship between RC and NAFLD was also identified.
Study context
- Population
- National Health and Nutrition Examination Survey 2017–2020 participants; Nonalcoholic fatty liver disease (NAFLD) diagnosed by ultrasonography
- Participants
- 3,370 participants
- Exposure
- Remnant cholesterol level and NAFLD
- Outcome
- NAFLD (ultrasonography-based) in relation to RC
Main finding
As reported in the abstract
Non-linear association; inflection point
0.96 mmol/l
Effect size left of inflection point (interval)
3.88
2.43 to 6.2
Effect size right of inflection point (interval)
0.59
0.21 to 1.71
Observational data: associations, not effects.
Further findings
Subgroup analysis: interaction factors
- Age, P for interaction
- 0.0309
- Waist circumference, P for interaction
- 0.0071
Original publication
Remnant cholesterol has a non-linear association with non-alcoholic fatty liver disease. Diabetes Res Clin Pract. Published 26 May 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →