Rebound Hyperglycemia in Children and Adolescents with Type 1 Diabetes Using Automated Insulin Delivery Systems
Authors' conclusion
In conclusion, RH was common and associated with adverse glucose outcomes.
Study context
- Population
- Children and adolescents <18 years with T1D using automated insulin delivery (AID) systems; mean age 11 ± 2 years, HbA1c 53.9 ± 10.3 mmol/mol, 84 females
- Participants
- 190 children
- Exposure
- Tandem Control-IQ vs Medtronic MiniMed 780G
- Control-IQ (CIQ)n = 94
- Outcome
- Frequency and severity of rebound hyperglycemia (sensor glucose (SG) >10.0 mmol/L within 2 h after hypoglycemia SG <3.9 mmol/L); severity as area under the SG-curve above 10.0 mmol/L
Methodological detailsreal-world
- Real-world
Main finding
As reported in the abstract
Hypoglycemia events per week (mean ± SD)
9.4 ± 5.5
Hypoglycemia events leading to rebound hyperglycemia (RH)
41%
Observational data: associations, not effects.
Further findings
Association of RH-severity with glucose metrics
- Greater RH-severity associated with lower TIR and higher glycemic variability
Original publication
Rebound Hyperglycemia in Children and Adolescents with Type 1 Diabetes Using Automated Insulin Delivery Systems. Diabetes Technol Ther. Published 10 July 2026. doi:10.
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