Glycemic Outcomes Following a Missed Premeal Bolus: A Comparative Study of Three Automated Insulin Delivery Systems in Children with Type 1 Diabetes
Authors' conclusion
AID systems differ in their capacity to compensate for missed premeal boluses. 780G and CIQ outperformed CamAPS in limiting postprandial hyperglycemia
Study context
- Population
- Children with T1D using automated insulin delivery (AID); 30 g and 50 g carbohydrates as standardized enteral nutrition with premeal bolus purposely omitted; mean age 13 years, mean HbA1c 47 mmol/mol (6.5%)completed the study
- Participants
- 43 children
- Exposure
- MiniMed 780G vs Tandem Control-IQ vs Ypsomed CamAPS (CamAPS) after a missed premeal bolus
- Outcome
- Mean AUC of glucose concentration change (30 g CH)
- Follow-up
- 4 h postprandially
Methodological detailscomparative
- Comparative
Main finding
As reported in the abstract
780G
137
mean · mmol/L·sec·103
Control-IQ (CIQ)
144
mean · mmol/L·sec·103
CamAPS
156
mean · mmol/L·sec·103
P < 0.01
Observational data: associations, not effects.
Further findings
Time in level 2 hyperglycemia (30 g CH) · 4 h postprandially — CamAPS vs 780G · CamAPS vs CIQ and 780G
P < 0.001
Time in level 2 hyperglycemia (50 g CH) · 4 h postprandially — CamAPS vs 780G · CamAPS vs CIQ and 780G
P < 0.001
Mean AUC of glucose concentration change (50 g carbohydrates (CH)) · 4 h postprandially
- Similar trends were seen after 50 g of CH
Original publication
Glycemic Outcomes Following a Missed Premeal Bolus: A Comparative Study of Three Automated Insulin Delivery Systems in Children with Type 1 Diabetes. Diabetes Technol Ther. Published 5 February 2026. doi:10.
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