Glycemic Responses to Two Different Exercise Modalities in Adolescents with Type 1 Diabetes Using Automated Insulin Delivery Systems: The AIDing Exercise Study
Authors' conclusion
When applying consensus guideline preexercise recommendations, both exercise modalities achieved generally stable glycemic outcomes; however, hypoglycemia remained a challenge across study visits. These findings highlight that current AID systems still fall short of ensuring safe glycemic responses during exercise.
Study context
- Population
- Adolescents with T1D using automated insulin delivery (AID) systems (12 MiniMed 780G, 12 Tandem Control-IQ), with consensus guideline preexercise preparatory measurescrossover
- Participants
- 24 adolescents
- Comparison
- HIIE vs moderate-intensity continuous exercise (MICE)
- Primary endpoint
- Continuous glucose monitoring (CGM)-derived TIR (3.9-10.0 mmol/L [70-180 mg/dL])
Methodological detailstwo-period, matched on age, sex and total daily dose across AID systems
- Two-period
- Matched on age, sex and total daily dose across AID systems
Primary result
As reported in the abstract
TIRCGM
P = 0.261
Further findings
TIRPG by AID system
- TIRPG higher during MICE in the MiniMed 780G group
Safety
Events
| Outcome | HIIE | MICE |
|---|---|---|
| Participants with hypoglycemia | 8 | 11 |
Participants with hypoglycemia
- By AID system, no difference in number of participants with hypoglycemia at either visit
Original publication
Glycemic Responses to Two Different Exercise Modalities in Adolescents with Type 1 Diabetes Using Automated Insulin Delivery Systems: The AIDing Exercise Study. Diabetes Technol Ther. Published 8 June 2026. doi:10.
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