Gestational diabetes & diabetes in pregnancy
Prevalence of preeclampsia and uterine arteries resistance in the different phenotypes of gestational diabetes mellitus
Authors' conclusion
The combined abnormal phenotype presents with the highest rate of preeclampsia and the most distinct pattern of uterine arteries resistance.
Study context
- Population
- Pregnant women with and without Gestational Diabetes Mellitus (GDM) per IADPSG criteria; uterine artery doppler in all three trimesters1,654 with GDM
- Participants
- 6,928 women
- Exposure
- GDM phenotypes vs no GDM
- No GDMn = 5,274reference
- Abnormal fasting (AF)n = 546
- APn = 781
- Abnormal combined (AC)n = 327
- Outcome
- Prevalence of preeclampsia
Main finding
As reported in the abstract
P < 0.001
Observational data: associations, not effects.
Further findings
Trajectory of uterine artery pulsatility index percentiles in women who developed preeclampsia · throughout pregnancy
- AC phenotype trajectory, statistically different from No GDM and AP
- b = 0.129
- No GDM and AP trajectories, respectively
- b = −0.015 and b = −0.016
- Linear regression
Original publication
Prevalence of preeclampsia and uterine arteries resistance in the different phenotypes of gestational diabetes mellitus. Diabetes Res Clin Pract. Published 15 December 2022. doi:10.
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