Gestational diabetes & diabetes in pregnancy
Gestational diabetes mellitus phenotypes defined by 75-g oral glucose tolerance test response patterns: associations with perinatal outcomes and persistent postpartum diabetes
Authors' conclusion
OGTT pattern-based phenotyping differentiates GDM subgroups in routine care, with differences in metabolic severity, treatment need, selected perinatal indicators, and postpartum diabetes risk, supporting targeted antenatal management and postpartum follow-up.
Study context
- Population
- Women with gestational diabetes mellitus (GDM) diagnosed by 75-g oral glucose tolerance test (OGTT) at 24–28 weeks' gestation (IADPSG), January 2020–May 2025; mean age 31.4 years, mean BMI 32.5 kg/m²
- Participants
- 251 women
- Exposure
- GDM phenotypes by 75-g OGTT response pattern
- Outcome
- Persistent postpartum diabetes
- Follow-up
- ≥ 12 weeks postpartum
Methodological detailssingle-center
- Single-center
Main finding
As reported in the abstract
Persistent postpartum diabetes, overall
12%
Observational data: associations, not effects.
Further findings
- Insulin therapy — Group 3
- 27.4%
- Insulin therapy — Insulin therapy most frequent in Group 3
- p < 0.001
HbA1c
- Higher HbA1c in Group 3
- P = 0.011
Delivery timing
- Earlier delivery in Group 3
- P = 0.008
Original publication
Gestational diabetes mellitus phenotypes defined by 75-g oral glucose tolerance test response patterns: associations with perinatal outcomes and persistent postpartum diabetes. Diabetes Res Clin Pract. Published 8 February 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →