Gestational diabetes & diabetes in pregnancy

Association of prior COVID-19 infection with gestational diabetes mellitus

Diabetes Res Clin PractPublished Retrospective matched cohort study

Main finding · GDM incidenceResult — go to the resultOdds ratio 0.75 95% CI 0.38–1.46

Authors' conclusion

COVID-19 infection in the preconception or early pregnancy period was not associated with increased incidence of GDM.

Study context

Population
Pregnant individuals aged 18 to 45, ≥24 weeks gestational age at delivery, delivering at two university affiliated hospitals 6/1/2021–12/31/2021; excluded pre-gestational DM, multiple gestation, cystic fibrosis or pancreatic insufficiencymatched cohort
Participants
182 vs 182
Exposure
Prior COVID-19 infection vs no prior infection
  • Casesn = 182
  • Controlsn = 182reference
Outcome
GDM diagnosis (two-step approach, Carpenter-Coustan criteria)
Methodological detailsmatched 1:1 by age and BMI, two university affiliated hospitals
  • Matched 1:1 by age and BMI
  • Two university affiliated hospitals

Main finding

GDM incidence

Odds ratio

0.75

95% CI 0.38–1.46

Casesvs Controls
OR 0.75 (95% CI 0.38–1.46)

As reported in the abstract

Observational data: associations, not effects.

Further findings

Gestational diabetes mellitus (GDM) by timing of COVID-19 infection

No differences in GDM incidence based on timing of COVID-19 infection
P = 0.097

Delivery method, obstetrical lacerations, Apgar scores

No differences in delivery method, obstetrical lacerations, or Apgar scores

Original publication

Association of prior COVID-19 infection with gestational diabetes mellitus. Diabetes Res Clin Pract. Published 6 February 2026. doi:10.1016/j.diabres.2026.113144

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