Gestational diabetes & diabetes in pregnancy

Pregnancy outcomes in the different phenotypes of gestational diabetes mellitus based on the oral glucose tolerance test. A systematic review and meta-analysis

Diabetes Res Clin PractPublished Systematic review and meta-analysis of cohort, cross-sectional and case-control studies

Authors' conclusion

Pregnant women with abnormal fasting plasma glucose, present with the highest prevalence of LGA, while those with abnormal combined plasma glucose, present with the highest prevalence of HDP. Pregnant women with abnormal post-load plasma glucose present with the lowest need for insulin treatment.

Study context

Population
Pregnant women with gestational diabetes mellitus (GDM) grouped by oral glucose tolerance test (OGTT) results
Participants
20.928 women8 studies
Comparison
GDM phenotypes by OGTT: abnormal fasting vs abnormal post-load vs abnormal combined plasma glucose
Outcome
LGA and hypertensive disorders of pregnancy (HDP)

Pooled result

As reported in the abstract

LGA pooled prevalence

HDP pooled prevalence

Further pooled results

Insulin treatment · pooled prevalence

Original publication

Pregnancy outcomes in the different phenotypes of gestational diabetes mellitus based on the oral glucose tolerance test. A systematic review and meta-analysis. Diabetes Res Clin Pract. Published 22 September 2023. doi:10.1016/j.diabres.2023.110913

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