Gestational diabetes & diabetes in pregnancy

Different subtypes of gestational diabetes mellitus are associated with distinct perinatal outcomes in twin pregnancies

Diabetes Res Clin PractPublished Retrospective cohort study

Authors' conclusion

Different subtypes of GDM are associated with distinct perinatal outcomes. Only abnormal fasting glucose levels may be responsible for reduced the risk of SGA neonates.

Study context

Population
Women with twin pregnancies giving birth at a tertiary hospital, January 2017–December 2022; Gestational diabetes mellitus (GDM) by IADPSG criteria
Exposure
GDM subtypes and perinatal outcomes
Outcome
Perinatal outcomes
Methodological detailssingle tertiary hospital
  • Single tertiary hospital

Main finding

As reported in the abstract

Perinatal outcomes by GDM subtype
OAPG: Preterm delivery (PTD) <37 weeks, aOR
1.22 (95% CI 1.01-1.47)
OAPG: Neonatalintensivecareunit (NICU) admission, aOR
1.31 (95% CI 1.09-1.57)
ACFPG: PTD <37 weeks, aOR
1.42 (95% CI 1.06-1.89)
ACFPG: PTD <34 weeks, aOR
1.65 (95% CI 1.14-2.39)
Only abnormal fasting glucose (OAFG): Small-for-gestational age (SGA), aOR
0.48 (95% CI 0.26-0.92)

Observational data: associations, not effects.

Original publication

Different subtypes of gestational diabetes mellitus are associated with distinct perinatal outcomes in twin pregnancies. Diabetes Res Clin Pract. Published 22 September 2023. doi:10.1016/j.diabres.2023.110920

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