Gestational diabetes & diabetes in pregnancy
Ethnic-specific oral glucose tolerance (oral glucose tolerance test (OGTT)) phenotypes in women with hyperglycemia in pregnancy
Authors' conclusion
Unique OGTT phenotypes exist across ethnic groups among women who developed HIP in a multi-ethnic Asian population.
Study context
- Population
- Women at KK Women's and Children's Hospital in 2019; Hyperglycemia in pregnancy (HIP) diagnosed by IADPSG criteria at 24–28 weeks; OGTT phenotypes: abnormal glucose at 0 hour only, 1 hour only, 2 hour only, or ≥2 timepoints (reference)508 with HIP
- Participants
- 3,027 women
- Exposure
- OGTT phenotypes by ethnicity
- Outcome
- Fasting-only OGTT phenotype
Methodological detailssingle-centre, multinomial logistic regression adjusted for maternal age, parity and first-trimester BMI
- Single-centre
- Multinomial logistic regression adjusted for maternal age, parity and first-trimester BMI
Main finding
As reported in the abstract
Relative risk ratio (RRR)
3.05
Indians · higher risk with Indians
RRR
2.33
Chinese · higher risk with Chinese
Observational data: associations, not effects.
Further findings
HIP prevalence · 24-28 weeks
| Outcome | RRR |
|---|---|
| 2-hour postprandial OGTT phenotypeChinese vs Malays · increased risk with Chinese | 2.88 |
- HIP prevalence — Overall HIP prevalence
- 508 (16.8%)
Original publication
Ethnic-specific oral glucose tolerance (OGTT) phenotypes in women with hyperglycemia in pregnancy. BMJ Open Diabetes Res Care. Published 4 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →