Gestational diabetes & diabetes in pregnancy
Early Postpartum Glucose Tolerance Reclassification by Gestational Diabetes Subtype
Authors' conclusion
In this cohort study, GD subtypes had distinct postpartum prediabetes risks. Early action and intervention to address dysglycemia may be most beneficial for women with fasting or mixed defects.
Study context
- Population
- Women with gestational diabetes (GD) (Carpenter and Coustan criteria, complete 3-hour 100-g oral glucose tolerance test (OGTT)) from SWIFT, Kaiser Permanente Northern California, 2008–2011; median age 33.2 years
- Participants
- 1,005 women
- Exposure
- GD subtypes by diagnostic OGTT: GD-F and GD-M vs GD-P
- GD-Pn = 616reference
- GD-Fn = 124
- GD-Mn = 265
- Outcome
- Postpartum prediabetes by 2-hour 75-g OGTT; adjusted prevalence ratios
- Follow-up
- 6 to 9 weeks after delivery
Methodological detailssecondary analysis of SWIFT cohort, modified Poisson regression, Data analyses January to July 2025
- Secondary analysis of SWIFT cohort
- Modified Poisson regression
- Data analyses January to July 2025
Main finding
As reported in the abstract
Postpartum prediabetes
Adjusted prevalence ratio (95% CI)P value
GD-Fvs GD-P
1.74(1.36–2.24)
P < 0.001GD-Mvs GD-P
2.23(1.85–2.68)
P < 0.001Between GD-M and GD-Fpairwise comparison between GD-F and GD-M; between
1.28(1.01–1.61)
P = 0.04- Overall prevalence of postpartum prediabetes
- 34.5% (347 women)
Observational data: associations, not effects.
Original publication
Early Postpartum Glucose Tolerance Reclassification by Gestational Diabetes Subtype. JAMA Netw Open. Published 3 November 2025. doi:10.
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