Prevalence and Trends of Thyroid Disease Among Adults, 1999-2018
Authors' conclusion
The age-standardized prevalence of thyroid disease among US adults increased from 1999-2003, remained stable between 2003 and 2014, and then saw an increase from 2014-2018, with the highest rate observed among elders, women, and non-Hispanic Whites.
Study context
- Population
- US adults, National Health and Nutrition Examination Survey (NHANES), January 1, 1999 to December 31, 2018; thyroid disease defined as self-reported thyroid disease on thyroid-related treatmentexamined
- Participants
- 57,540 adults
- Outcome
- Age-standardized prevalence of thyroid disease
- Follow-up
- 4-year survey periods (1999-2002, 2003-2006, 2007-2010, 2011-2014, and 2015-2018)
Methodological detailsnationally representative, NHANES 1999–2018, 4-year survey periods
- Nationally representative
- NHANES 1999–2018
- 4-year survey periods
Main finding
As reported in the abstract
2015-2018
- Age-standardized prevalence 2015-2018
- 5.05% (95% CI 4.55%-5.60%)
- Significant increase from 1999-2002 period
- P <.0002
Observational data: associations, not effects.
Further findings
Prevalence by subgroup
- Non-Hispanic Whites
- 8.1% (highest; 95% CI 7.3%-9.0%)
- Aged ≥60 years
- 15.4% (highest; 95% CI 13.3%-17.8%)
- Women
- 7.6% (tended to be higher; 95% CI 6.8%-8.5%)
Factors associated with thyroid disease (multiple regression)
- Age, women sex, non-Hispanic White and Mexican American, BMI, higher education and incomes independently associated with increased risk of thyroid disease
Original publication
Prevalence and Trends of Thyroid Disease Among Adults, 1999-2018. Endocr Pract. Published 22 August 2023. doi:10.
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