Effect of Roxadustat on Thyroid Function in Patients With Renal Anemia
Authors' conclusion
Roxadustat decreases TSH and FT4 levels while daprodustat does not.
Study context
- Population
- Patients with anemia in chronic kidney disease (CKD) treated with roxadustat or daprodustat
- Participants
- 26 patients
- Exposure
- Roxadustat vs daprodustat
- Outcome
- Thyroid-stimulating hormone (TSH) and free thyroxine (FT4) before and after treatment
Main finding
As reported in the abstract
- Roxadustat after vs Roxadustat before: P < 0.05
- Roxadustat after vs Roxadustat before: P < 0.01
- Daprodustat after vs Daprodustat before: P = 0.635
- Daprodustat after vs Daprodustat before: P = 0.328
Observational data: associations, not effects.
Original publication
Effect of Roxadustat on Thyroid Function in Patients With Renal Anemia. J Clin Endocrinol Metab. Published 19 August 2023. doi:10.
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