Obesity

Predicting high‐risk periods for weight regain following initial weight loss

Obesity (Silver Spring)Published Prognostic model development and validation study

Authors' conclusion

Weight regain can be predicted on a proximal, week-to-week level. Future work should investigate the clinical utility of adaptive interventions for weight-loss maintenance and develop more sophisticated predictive models of weight regain.

Study context

Population
Adults after initial weight loss; weekly questionnaire and self-monitoring data (incl. daily e-scale) over 40 weeks
Participants
46 / 22 / 30
Comparison
Training (Study 1, ≥5% loss) vs Testing (Study 1, <5% loss) vs Testing (Study 2)
  • Training (Study 1, ≥5% loss)n = 46
  • Testing (Study 1, <5% loss)n = 22
  • Testing (Study 2)n = 30
Outcome
Prediction of weight regain the following week (week-to-week)
Methodological detailslongitudinal mixed-effects models, random forest regression, external testing data sets
  • Longitudinal mixed-effects models
  • Random forest regression
  • External testing data sets

Performance

As reported in the abstract

Prediction of weight regain the following week
Test or modelSensitivitySpecificity
Initial training data set75.6%45.8%
Testing data sets81%-82%30%-33%

Sensitivity

Initial training data set75.6%
Testing data sets81%-82%

Specificity

Initial training data set45.8%
Testing data sets30%-33%

Further findings

Predictors retained in final algorithm

Frequency of self-monitoring caloric intake and weight, plus self-rated hunger and importance of weight-management goals vs competing life demands

Original publication

Predicting high‐risk periods for weight regain following initial weight loss. Obesity (Silver Spring). Published 2 November 2023. doi:10.1002/oby.23923

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