Obesity

Sex-Specific Obesity and Cardiometabolic Disease Risks in Low- and Middle-Income Countries: A Meta-Analysis Involving 3 916 276 Individuals

J Clin Endocrinol MetabPublished Systematic review and meta-analysis

Pooled result · ObesityResult — go to the resultOdds ratio 2.72 95% CI 2.54–2.91

Authors' conclusion

There is an urgent need for a women-centred and region-stratified approach to tackle obesity awareness, treatment, and prevention in women in LMICs.

Study context

Population
Individuals in low- and middle-income countries (LMICs); databases searched from inception to March 2023
Participants
3,916,276 individuals345 studies
Comparison
Women vs men
Outcome
Sex-specific disparities in the prevalence of obesity
Methodological detailsDerSimonian and Laird random-effects models, multilevel random-effects logistic regression, Two independent reviewers selected studies, assessed quality and extracted data
  • DerSimonian and Laird random-effects models
  • Multilevel random-effects logistic regression
  • Two independent reviewers selected studies, assessed quality and extracted data

Pooled result

Obesity

Odds ratio

2.72

95% CI 2.54–2.91

Womenvs Men
OR 2.72 (95% CI 2.54–2.91)

As reported in the abstract

Further pooled results

OutcomeEstimate
Obesity, Sub-Saharan Africa (region with greatest sex disparity)OR 3.91 (95% CI 3.49–4.39)
Hypertension and T2D in women with vs without obesityWomen with obesityvs Women without obesityOR (hypertension) 2.41 (95% CI 1.89–3.08)
Hypertension and T2D in women with vs without obesityWomen with obesityvs Women without obesityOR (T2D) 2.65 (95% CI 1.76–3.98)

Prevalence among women in LMICs

Obesity
23% (95% CI, 21%-25%)
Hypertension
27% (95% CI, 24%-29%)
T2D
7% (95% CI, 6%-9%)
Prevalence of obesity and T2D in women varied by region, country's income and setting, highest in Middle East and North Africa, upper-middle-income countries and urban settings

Original publication

Sex-Specific Obesity and Cardiometabolic Disease Risks in Low- and Middle-Income Countries: A Meta-Analysis Involving 3 916 276 Individuals. J Clin Endocrinol Metab. Published 1 November 2023. doi:10.1210/clinem/dgad599

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