Partial starch substitution with resistant starch lowers postprandial glucose and glycaemic variability in people with type 2 diabetes
Authors' conclusion
Substituting a proportion of starch with RS lowers blood glucose without changing the sensory attributes of foods significantly. There is potential to develop a functional diet for adults with type 2 diabetes to aid glycaemic control.
Study context
- Population
- Adults with T2D; HbA1c 52 ± 2 mmol/mol (6.9 ± 0.3%), age 58 ± 11 years95% completed arms
- Participants
- 20 adults
- Comparison
- Resistant starch (RS) diet vs control diet, 4 days each
Methodological detailssingle-blinded, free-living setting
- Single-blinded
- Free-living setting
Primary result
As reported in the abstract
Glycaemic measures (CGM) · 4-day diets
- Mean amplitude of glycaemic excursion (MAGE) over lunch; lower with RS
- difference 0.94 mmol/L; P = 0.004
- SD glucose over lunch; lower with RS
- difference 0.31 mmol/L; P = 0.027
- Peak glucose over lunch; lower with RS
- difference 0.94 mmol/L; P = 0.028
- Time to glucose peak at lunch; longer with RS
- difference 18 min; P = 0.046
- Time to glucose peak at dinner; longer with RS
- difference 28 min; P = 0.002
- Time in range (TIR) (glucose 3.9-10.0 mmol/L); greater with RS
- difference 7.8%; P = 0.021
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Partial starch substitution with resistant starch lowers postprandial glucose and glycaemic variability in people with type 2 diabetes. Diabet Med. Published 9 July 2025. doi:10.
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