Exercise snacks performed in real-world settings reduce postprandial hyperglycaemia and glycaemic variability in individuals living with type 2 diabetes: a randomised crossover study
Primary result · Mean glucoseResult — go to the resultBetween-condition difference −0.2 mmol/l 95% CI −0.4 to 0.0Authors' conclusion
Bodyweight exercise snacks totalling 4 min of vigorous activity per day led to small, yet statistically significant improvements in indices of glycaemic variability and postprandial hyperglycaemia in insufficiently active individuals living with well-controlled type 2 diabetes.
Study context
- Population
- Previously inactive adults with well-controlled, non-insulin-treated T2D; 21 female, 10 male; ≈58 years, BMI ≈31 kg/m², HbA1c ≈48 mmol/mol [6.6%]crossover
- Participants
- 31 adults
- Comparison
- Exercise snacks vs no-exercise control
- Primary endpoint
- Mean glucose by CGM during each condition
- Follow-up
- 48 h
Methodological detailscounterbalanced order, real-world setting, standardised diet
- Counterbalanced order
- Real-world setting
- Standardised diet
Primary result
Mean glucose
Between-condition difference
−0.2 mmol/l
95% CI −0.4 to 0.0
P = 0.07
ESvs CON
between-condition difference −0.2 mmol/l (95% CI −0.4 to 0.0); P = 0.07
As reported in the abstract
Secondary outcomes
| Outcome | Difference (mmol/l) (95% CI) | P value | |
|---|---|---|---|
| Glucose SD | −0.1 (−0.2 to −0.1) | P < 0.001 | |
| Mean amplitude of glycaemic excursions | −0.3 (−0.5 to 0.0) | P = 0.04 | |
| −0.6−0.4−0.200.2Difference, mmol/l (linear scale) |
| Outcome | Difference (%) (95% CI) | P value | |
|---|---|---|---|
| Glucose CV | −1 (−2 to 0) | P = 0.007 | |
| Time in tight range | 3 (0–6) | P = 0.04 | |
| −50510Difference, % (linear scale) |
| Outcome | P value |
|---|---|
| 2 h postprandial glucose (average, peak, AUC, incremental AUC) after breakfast and dinner | all p<0.05 |
2 h postprandial glucose (average, peak, AUC, incremental AUC) after breakfast and dinner
- Significantly lower during ES vs condition (CON)
Original publication
Exercise snacks performed in real-world settings reduce postprandial hyperglycaemia and glycaemic variability in individuals living with type 2 diabetes: a randomised crossover study. Diabetologia. Published 24 April 2026. doi:10. 1007/ s00125-026-06741-2
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