Type 2 & other diabetes

Exercise snacks to combat hyperglycaemia in patients with abnormal glycaemic control: Use of a novel strategy based on individual continuous glucose data in a real-world setting

Diabetes Res Clin PractPublished Randomised crossover trial

Authors' conclusion

The results suggest that regular ES reduce time in individual hyperglycaemia more effectively than a single long exercise session. CGM-ES may enhance motivation and facilitate rapid attenuation of hyperglycaemia in a real-world setting.

Study context

Population
Individuals with abnormal glycaemic control (HbA1c ≥ 5.7%), aged 56 ± 10 years, real-world setting
Participants
25 individuals
Comparison
Continuous glucose monitoring (CGM)-guided exercise snacks vs fixed-time exercise snacks (ES) vs single long exercise session vs no exercise
Primary endpoint
Time in individual hyperglycaemia
Follow-up
72 h
Methodological detailsfour consecutive 3-day experimental periods, 4-day washout periods, real-world setting
  • Four consecutive 3-day experimental periods
  • 4-day washout periods
  • Real-world setting

Primary result

As reported in the abstract

  • Reduced by approximately one third in both CGM-ES and NON-CGM-ES vs CONTROL or SINGLE-EX
  • CONTROL: P < 0.001

Further findings

OutcomeCGM-ESNON-CGM-ESSINGLE-EX
Adherence85%88%93%
Intention to continue (5-point Likert scale) · CGM-ES vs CONTROL · difference between CGM-ES, NON-CGM-ES and SINGLE-EX
P = 0.042

Intention to continue (5-point Likert scale)

CGM-ES and SINGLE-EX showed the highest mean scores

Original publication

Exercise snacks to combat hyperglycaemia in patients with abnormal glycaemic control: Use of a novel strategy based on individual continuous glucose data in a real-world setting. Diabetes Res Clin Pract. Published 14 June 2026. doi:10.1016/j.diabres.2026.113374

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