Gestational diabetes & diabetes in pregnancy
Offspring sex modifies the association between early-pregnancy adiposity and 2-year-old physical activity—The Glowing Study
Main finding · Association of maternal FMI with 2-yo-PAResult — go to the resultβ −1.14 CI −2.1 to −0.18Authors' conclusion
The association of 2-yo-PA and early pregnancy maternal adiposity was modified by offspring sex. Offspring's physical activity decreased with increasing early pregnancy adiposity maternal in girls but not boys in second parity dyads.
Study context
- Population
- Women enrolled early in pregnancy (<10 weeks) and their offspring followed to age 2 years
- Participants
- 153 women
- Exposure
- Maternal early-pregnancy fat mass index (FMI) vs offspring physical activity (PA) at 2 years, by offspring sex
- Outcome
- Offspring PA (accelerometers; average activity counts (AC)4/day) in association with maternal FMI
- Follow-up
- Age 2 years
Main finding
Association of maternal FMI with 2-yo-PA
β
−1.14
CI −2.1 to −0.18
P = 0.02
As reported in the abstract
- Bivariate association of maternal FMI with 2-yo-PA, β
- −0.22 (CI −0.73 to 0.29, p = 0.398)
- Girls: 2-yo-PA vs maternal FMI, β
- −0.82 (CI −1.43 to 0.29, p = 0.009)
- Boys: 2-yo-PA vs maternal FMI, β
- 0.32 (CI −0.38 to 1.01, p = 0.376)
Observational data: associations, not effects.
Original publication
Offspring sex modifies the association between early-pregnancy adiposity and 2-year-old physical activity—The Glowing Study. Int J Obes (Lond). Published 20 January 2024. doi:10.
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