Gestational diabetes & diabetes in pregnancy
REduced‐Carbohydrate intervention for managing Obesity and Reduction of gestational Diabetes ( RECORD ): A randomized controlled feasibility trial
Authors' conclusion
Retention was high, suggesting the study processes are feasible, but the carbohydrate reduction in the intervention group was small, and did not meet progression criteria, limiting the likelihood of achieving the desired goal to prevent gestational diabetes.
Study context
- Population
- Pregnant women at <20 weeks' gestation with BMI ≥30 kg/m² and a normal baseline oral glucose tolerance test (OGTT)randomized 2:1
- Participants
- 51 women
- Comparison
- Reduced-carbohydrate dietary program vs control
- Primary endpoint
- Feasibility: adoption of the reduced-carbohydrate diet by the intervention group, and retention of all participants (completion of a second OGTT)
- Follow-up
- 24-28 weeks' gestation
Methodological detailsrandomized 2:1
- Randomized 2:1
Primary result
As reported in the abstract
Retention (attended follow-up OGTT); carbohydrate intake in the intervention group
| Group | Value | Change from baseline (95% CI −51.5-2.4) |
|---|---|---|
| Intervention | 190.4 (CI 162.5–215.6) g/day | −24.6 g/day |
Intervention
Value190.4 (CI 162.5–215.6) g/day
Change from baseline (95% CI −51.5-2.4)−24.6 g/day
- Retention: 49 of 51 attended follow-up OGTT
- 96% (95% CI 86.8%-98.9%)
Further findings
Glucose control, weight gain and blood pressure
- Potentially favourable effects of the intervention observed; study not powered to detect significant differences
Acceptability
- Participants found the intervention acceptable and were content with study processes; some reported barriers to sustained adherence, mainly competing priorities
Original publication
REduced‐Carbohydrate intervention for managing Obesity and Reduction of gestational Diabetes ( RECORD ): A randomized controlled feasibility trial. Diabetes Obes Metab. Published 16 January 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →