Normal-weight visceral obesity promotes a higher 10-year atherosclerotic cardiovascular disease risk in patients with type 2 diabetes mellitus–a multicenter study in China
Authors' conclusion
T2DM patients with normal-weight visceral obesity had a higher 10-year ASCVD risk than BMI-defined overweight or obese counterparts with or without visceral obesity, which should initiate standardised management for ASCVD primary prevention.
Study context
- Population
- Patients with T2DM, China; separated into six groups by body mass index (BMI) and visceral fat area (VFA)six BMI/VFA groups
- Participants
- 6,997 patients
- Exposure
- Combinations of BMI category and visceral obesity
- Outcome
- High 10-year ASCVD risk
Main finding
As reported in the abstract
- Normal-weight visceral obesity had the highest 10-year atherosclerotic cardiovascular disease (ASCVD) risk among the six groups, with >2-fold or 3-fold higher OR than overweight or obese (by BMI) without visceral obesity (all P < 0.05)
Observational data: associations, not effects.
Further findings
VFA threshold for high 10-year ASCVD risk
- VFA threshold
- 90 cm²
Factors affecting VFA (multilinear regression)
- Age, hypertension, drinking, fasting serum insulin, FPG, 2 h postprandial C-peptide, TG, total cholesterol, HDL-C and LDL-C significantly affected VFA (all P < 0.05)
Original publication
Normal-weight visceral obesity promotes a higher 10-year atherosclerotic cardiovascular disease risk in patients with type 2 diabetes mellitus–a multicenter study in China. Cardiovasc Diabetol. Published 12 June 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →