Gestational diabetes & diabetes in pregnancy
National trends in offspring birth size in pregnancies with maternal type 1 diabetes in Sweden
Authors' conclusion
There was no improvement over a 20-year period in the distributions of birth weights or PÍs in offspring of T1D mothers in Sweden, unrelated to maternal BMI. Overall, 61% of offspring of T1D mothers were LGA.
Study context
- Population
- All live-born infants to T1D mothers between 1998 and 2016 across Swedenoffspring of T1D mothers
- Participants
- 6,485 infants
- Exposure
- Period 2 vs period 1
- Outcome
- Percentiles of birthweight (BW) and ponderal index (PI)
Methodological detailsnational registers, quantile regression, adjusted for maternal characteristics and hypertensive disease
- National registers
- Quantile regression
- Adjusted for maternal characteristics and hypertensive disease
Main finding
As reported in the abstract
Distributions of BW and PI
- Birthweights (BW) and ponderal index (PI) distributions did not change between the two periods, neither for the heaviest infants (LGA) nor for the smallest, independent of maternal first trimester BMI
Observational data: associations, not effects.
Further findings
- Proportion of LGA remained at
- 61%
Original publication
National trends in offspring birth size in pregnancies with maternal type 1 diabetes in Sweden. Diabetes Res Clin Pract. Published 26 June 2025. doi:10.
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