Gestational diabetes & diabetes in pregnancy
Comparison of maternal characteristics and clinical parameters in Thai pregnant women with and without gestational diabetes mellitus
Authors' conclusion
These findings underscore distinct clinical and biochemical profiles in Thai women with GDM, emphasizing the need for early detection and targeted interventions to mitigate associated risks.
Study context
- Population
- Thai pregnant women attending antenatal care at Siriraj Hospital, Thailand
- Participants
- 825 women
- Exposure
- Pregnant women with Gestational Diabetes Mellitus (GDM) vs without GDM
- GDMn = 141
- Non-GDMn = 684reference
- Outcome
- Maternal characteristics and clinical parameters in women with vs without GDM
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
- Women with GDM were significantly older, had higher gestational age at diagnosis, higher pre-pregnancy BMI and higher systolic and diastolic BP
- Family history of diabetes and comorbidities more prevalent with GDM
- Significant differences in white blood cell counts, particularly neutrophils and lymphocytes
- Higher alanine transaminase and HbA1c with GDM
Observational data: associations, not effects.
Further findings
Independent risk factors for GDM (multivariable)
- Diastolic blood pressure, aOR
- 1.036 (95 % CI 1.008-1.064, p = 0.01)
- Presence of comorbidities, aOR
- 9.027 (95 % CI 5.573-14.621, p < 0.001)
Laboratory findings
- Significant differences in white blood cell counts, particularly neutrophils and lymphocytes
- Elevated alanine transaminase and HbA1c in GDM
Original publication
Comparison of maternal characteristics and clinical parameters in Thai pregnant women with and without gestational diabetes mellitus. Diabetes Res Clin Pract. Published 21 June 2025. doi:10.
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