Gestational diabetes & diabetes in pregnancy
Gestational diabetes risk associated with early pregnancy blood pressure characteristics and trajectories: A Chinese prospective cohort study
Authors' conclusion
Poor early pregnancy BP characteristics and unfavourable BP trajectories are associated with an elevated risk of GDM. These findings suggest that monitoring BP throughout early pregnancy could serve as an essential strategy for identifying women at higher risk for GDM, potentially enabling timely preventative measures.
Study context
- Population
- Pregnant women, Shenzhen Maternity and Child Healthcare Hospital, China; Blood pressure (BP) at initial prenatal visit, systolic blood pressure (SBP) trajectories up to 20 weeks' gestation
- Participants
- 16,020 women
- Exposure
- Early pregnancy BP characteristics and SBP trajectories vs reference categories
- Outcome
- GDM
Main finding
As reported in the abstract
GDM risk
Each group vs low-stableOdds ratio (95% CI)
Moderate BP
1.24(1.14–1.35)
Isolated moderate SBP
1.27(1.16–1.38)
Early pregnancy hypertension
1.32(1.02–1.71)
- Medium-stable
- OR 1.31; all p < 0.01
- Medium-high stable
- OR 1.61; all p < 0.01
- Peak pattern
- OR 1.98; all p < 0.01
- Developed gestational diabetes mellitus (GDM)
- 23.91% (3830/16 020)
- SBP, each 10 mmHg increase: OR
- 1.14 (1.10-1.18) (95% CI)
- Diastolic blood pressure (DBP), each 5 mmHg: OR
- 1.07 (1.05-1.09)
- Pulse pressure (PP), each 5 mmHg: OR
- 1.04 (1.02-1.07)
- Highest vs lowest PP tertile: OR
- 1.20 (1.09-1.32)
Observational data: associations, not effects.
Original publication
Gestational diabetes risk associated with early pregnancy blood pressure characteristics and trajectories: A Chinese prospective cohort study. Diabetes Obes Metab. Published 19 June 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →