Gestational diabetes & diabetes in pregnancy
Treatment of Gestational Diabetes Mellitus and Maternal Risk of Diabetes After Pregnancy
Authors' conclusion
Treating GDM lowers birth weight but does not disrupt the association between gestational glycemia and maternal prediabetes/diabetes after pregnancy.
Study context
- Population
- Women with metabolic testing at 3 and 12 months postpartum, by gestational glucose tolerance
- Participants
- 599 women
- Exposure
- Gestational glucose tolerance groups, including mild untreated gestational diabetes mellitus (GDM) vs severe treated GDM
- Outcome
- Postpartum glucose tolerance
- Follow-up
- 3 and 12 months postpartum
Main finding
As reported in the abstract
Prevalence of prediabetes/diabetes · 12 months postpartum
Prediabetes/diabetes at 12 months, groups 1-5 respectively (stepwise increase; P < 0.0001)
2.8%, 9.6%, 13.5%, 21.5%, and 32.6%
Observational data: associations, not effects.
Further findings
Insulin sensitivity, β-cell function, fasting and 2-h glucose · 3 and 12 months
- Insulin sensitivity and β-cell function progressively decreased across the five groups, with rising fasting and 2-h glucose
- all P < 0.0001
Birth weight
- Birth weight progressively increased across groups 1-4, then fell steeply in treated GDM
- P < 0.0001
Original publication
Treatment of Gestational Diabetes Mellitus and Maternal Risk of Diabetes After Pregnancy. Diabetes Care. Published 5 January 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →