Gestational diabetes & diabetes in pregnancy
Miscarriage, stillbirth and the risk of diabetes in women: A systematic review and meta-analysis
Authors' conclusion
A history of miscarriage or stillbirth was associated with an increased risk of diabetes in women. Future studies are needed to explore whether prediabetic metabolic conditions contribute to this association.
Study context
- Population
- Women; studies from PubMed, Web of Science and Scopus through November 202213 cohort, 8 case-control studies
- Participants
- 529,990 women
- Comparison
- History of miscarriage or stillbirth vs none
- Outcome
- Risk of diabetes (non-gestational and gestational)
Methodological detailsrandom-effects model
- Random-effects model
Pooled result
As reported in the abstract
Diabetes risk
Estimate (95% CI)
Miscarriagevs No miscarriage
OR (non-gestational diabetes) 1.15(1.02–1.28)
Miscarriagevs No miscarriage
OR (GDM) 1.62(1.32–1.98)
Stillbirthvs No stillbirth
OR (non-gestational diabetes) 1.21(1.03–1.41)
Stillbirthvs No stillbirthno stable association
OR (GDM) 1.91(1.00–3.64)
Further pooled results
| Outcome | OR (95% CI) | |
|---|---|---|
| Non-gestational diabetes with ≥3 miscarriages≥3 miscarriagesvs No miscarriage | 1.99 (1.36–2.91) | |
| 0.20.5125Odds ratio (log scale) |
Original publication
Miscarriage, stillbirth and the risk of diabetes in women: A systematic review and meta-analysis. Diabetes Res Clin Pract. Published 17 December 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →