Obesity

Mediterranean diet vs. the Australian guide to healthy eating ( Australian Guide to Healthy Eating (AGHE) ) on body composition and glucose metabolism: A randomized controlled trial

Diabetes Obes MetabPublished Randomised controlled trial

Authors' conclusion

The Mediterranean diet demonstrated greater efficacy in improving body composition and maintaining metabolic variables than the AGHE. These findings may support the use of the Mediterranean diet in improving health outcomes related to obesity and metabolic disorders. However, larger, well-designed clinical trials are needed to confirm these findings and explore underlying mechanisms.

Study context

Population
Adults, median age 31 (IQR 25–37) years, 71.9% female, BMI = 25.1 kg/m²
Participants
57 adults
Comparison
Mediterranean diet vs AGHE diet
  • Mediterranean dietn = 23
  • AGHEn = 34reference
Primary endpoint
Body composition and glucose metabolism
Follow-up
Eight weeks

Primary result

As reported in the abstract

Mediterranean diet
difference in waist circumference −1.3 cm; P = 0.043
Mediterranean diet
difference in body fat percentage −1.8 %; P = 0.014
Mediterranean diet
difference in resting metabolic rate (RMR) −17.9 kcal/day; P = 0.02
Mediterranean diet
difference in fasting insulin −1.2 μIU/mL; P = 0.016
Mediterranean diet
difference in body lean mass percentage 1.7 %; P = 0.015

Original publication

Mediterranean diet vs. the Australian guide to healthy eating ( AGHE ) on body composition and glucose metabolism: A randomized controlled trial. Diabetes Obes Metab. Published 20 June 2025. doi:10.1111/dom.16458

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