Obesity

Time‐restricted eating, caloric reduction, and unrestricted eating effects on weight and metabolism: a randomized trial

Obesity (Silver Spring)Published Randomised controlled trial

Authors' conclusion

In a 12-week intervention, TRE did not lead to significant improvements in weight, average body composition, or glycemic or metabolic measures compared with CR or UE.

Study context

Population
Adults; mean age 43.2 (SD 10.5) years, BMI 36.2 (SD 5.1) kg/m²; 54.5% female, 84.1% White81 completed
Participants
88 adults
Comparison
8-h time-restricted eating (TRE) vs 15% caloric restriction (CR) vs unrestricted eating (UE)
  • TREn = 30
  • CRn = 29
  • UEn = 29reference
Primary endpoint
Weight
Follow-up
12 weeks

Primary result

As reported in the abstract

Weight change
Each group vs UEWeight change, kg (95% CI)P value
TRE
−1.4(−4.5 to 1.7)
P = 0.53
CR
−2.5(−5.8 to 0.8)
P = 0.18

Further findings

Final eating window · 12 weeks

OutcomeDifference (95% CI)
Metabolic flexibilityTREvs CR−0.041 (−0.080 to −0.002)

Weight, body composition, caloric intake, glycemic measures

Similar among groups
Eating window reduction correlated with decreased caloric intake and visceral fat

Original publication

Time‐restricted eating, caloric reduction, and unrestricted eating effects on weight and metabolism: a randomized trial. Obesity (Silver Spring). Published 19 February 2025. doi:10.1002/oby.24252

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