The effects of time‐restricted eating and weight loss on bone metabolism and health: a 6‐month randomized controlled trial
Authors' conclusion
TRE had no detrimental impact on bone health, whereas, when weight loss occurred, it was associated with some bone-sparing effects compared with SDA.
Study context
- Population
- Adults with ≥1 component of metabolic syndrome; 76% women, median age 47 years (IQR 31–52)
- Participants
- 42 adults
- Comparison
- Time-restricted eating (TRE) vs standard dietary advice (SDA)
- Primary endpoint
- Bone health: bone turnover markers and bone mineral content/density by DXA
- Follow-up
- 6-month follow-up
Primary result
As reported in the abstract
Bone parameters (total population) · 6 months
- No between-group differences (TRE vs SDA) in any bone parameter
Further findings
| Outcome | P value |
|---|---|
| CTX in weight loss responders (≥0.6 kg weight loss)Tended to decrease after TRE, increase after SDA | between-group differences p = 0.041 |
| Total body bone mineral content in weight loss responders | between-group differences p = 0.028 |
- Total body bone mineral content in weight loss responders — Decreased after SDA
- p = 0.028
- Total body bone mineral content in weight loss responders — Unchanged after TRE
- p = 0.31
P1NP changes in weight loss responders
- Changes in P1NP did not differ between groups
Bone outcomes in nonresponders (<0.6 kg weight loss)
- No between-group differences in bone outcomes
Original publication
The effects of time‐restricted eating and weight loss on bone metabolism and health: a 6‐month randomized controlled trial. Obesity (Silver Spring). Published 14 October 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →