Short‐term complications and post‐acute sequelae in hospitalized paediatric patients with COVID‐19 and obesity: A multicenter cohort study
Authors' conclusion
In paediatric hospitalized patients with COVID-19, severe short-term outcomes and post-acute sequelae are associated with obesity. Recognizing obesity as a key comorbidity is essential to develop targeted strategies for prevention of COVID-19 complications in children.
Study context
- Population
- Hospitalized paediatric patients with SARS-CoV-2 RT-PCR-confirmed COVID-19, 3 tertiary hospitals, March 2020–December 202167 (31.02%) with obesity
- Participants
- 216 patients
- Exposure
- Obesity vs no obesity
- Obesityn = 67
- Outcome
- Short-term outcomes: ICU admission, ventilatory support, superinfections, acute kidney injury and mortality; post-acute sequelae beyond 4 weeks from symptom onset
Methodological detailsobservational, three tertiary hospitals
- Observational
- Three tertiary hospitals
Main finding
As reported in the abstract
Short-term complications
Each group vs no obesityEstimate (95% CI)
Obesity
aOR (ICU admission) 5.63(2.90–10.94)
Obesity
aOR (oxygen requirement) 2.77(1.36–5.63)
Obesity
aOR (non-invasive ventilatory support) 6.81(2.11–22.04)
Obesity
aOR (overall superinfections) 3.02(1.45–6.31)
Obesity
aOR (suspected bacterial pneumonia) 3.00(1.44–6.23)
Observational data: associations, not effects.
Further findings
| Outcome | Estimate | |
|---|---|---|
| Post-acute sequelae · beyond 4 weeks from symptom onsetObesityvs No obesity | aOR (dyspnea) 9.91 (95% CI 1.92–51.10) | |
| Post-acute sequelae · beyond 4 weeks from symptom onsetObesityvs No obesity | aOR (muscle weakness) 20.04 (95% CI 2.50–160.65) | |
| 0.050.21520Ratio (log scale) |
Original publication
Short‐term complications and post‐acute sequelae in hospitalized paediatric patients with COVID‐19 and obesity: A multicenter cohort study. Pediatr Obes. Published 12 October 2022. doi:10.
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