Obesity

BMI and mortality in critically ill patients with COVID‐19: another brick in the wall of the obesity paradox

Obesity (Silver Spring)Published Retrospective cohort study

Authors' conclusion

Obesity was not associated with higher mortality rates in critically ill patients with COVID-19. Moreover, patients with BMI < 25 kg/m2 had a higher mortality rate compared with those in higher BMI categories.

Study context

Population
Adults aged ≥18 years admitted to the ICU with SARS-CoV-2, March 2020 to December 2021868 analysed
Participants
977 adults
Exposure
Obesity vs no obesity
  • Obesityn = 382
Outcome
In-hospital mortality
Methodological detailsmulticentre, Data from electronic medical records, Multiple logistic regression and restricted cubic splines analyses
  • Multicentre
  • Data from electronic medical records
  • Multiple logistic regression and restricted cubic splines analyses

Main finding

As reported in the abstract

P = 0.06

Overall in-hospital mortality
48%

Observational data: associations, not effects.

Further findings

Prone positioning

P < 0.001

Use of vasoactive medications

P < 0.001

Original publication

BMI and mortality in critically ill patients with COVID‐19: another brick in the wall of the obesity paradox. Obesity (Silver Spring). Published 30 June 2024. doi:10.1002/oby.24069

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