Body mass index changes and their association with SARS-CoV-2 infection: a real-world analysis
Authors' conclusion
In a diverse real-world cohort of adults, mean BMI of those with and without SARS-CoV2 infection varied in their trajectories. The mechanisms and implications of weight retention following SARS-CoV-2 infection remain unclear.
Study context
- Population
- Individuals aged 18–99 years, OneFlorida+ Clinical Research Network; 62% women, mean age 51.9 years (SD 18.9)
- Participants
- 249,743 individuals
- Exposure
- SARS-CoV-2 Exposed vs contemporary Unexposed vs Historical control cohorts
- Outcome
- BMI (kg/m²) at start of follow-up and change per 100 days of follow-up
Methodological detailsreal-world data, target trial approaches, age/sex-matched historical control cohort
- Real-world data
- Target trial approaches
- Age/sex-matched historical control cohort
Main finding
As reported in the abstract
BMI at start of follow-up
Unexposed
29.3
mean · 95% CI 29.1–29.4 · kg/m²
Each group vs unexposedDifference in mean BMI, kg/m2 (95% CI)
Exposed
0.07(0.01–0.12)
Historical
−0.20(−0.25 to −0.15)
Observational data: associations, not effects.
Further findings
kg/m²
| Outcome | Exposed | Unexposed | Historical |
|---|---|---|---|
| BMI change over 100 days | 0 (95% CI −0.03–0.03) | −0.04 (95% CI −0.05–-0.02) | 0.03 (95% CI 0.01–0.04) |
Subgroups (sex, race & ethnicity, age, hospitalization)
- Differences between Unexposed and Exposed consistent for most subgroups, except at start of follow-up among Males and those ≥65 years, who had lower body mass index (BMI) among Exposed
Original publication
Body mass index changes and their association with SARS-CoV-2 infection: a real-world analysis. Int J Obes (Lond). Published 14 September 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →