Ultra‐processed foods cause weight gain and increased energy intake associated with reduced chewing frequency: A randomized, open‐label, crossover study
Primary result · Body weight changeResult — go to the resultDifference 1.1 kg 95% CI 0.2–2.0Authors' conclusion
Consumption of UPFs causes significant weight gain. Medical nutritional therapy focused on reducing the consumption of UPFs could be an effective strategy for preventing obesity.
Study context
- Population
- Overweight/obese Japanese men without diabetes, hypertension or other regularly treated conditions; University of Tokyo Hospitalall completed
- Participants
- 9 men
- Comparison
- UPF diet vs non-UPF diet
- Primary endpoint
- Difference in body weight change between UPF and non-UPF periods
- Follow-up
- 1 week per period
Methodological detailsopen-label, crossover, single-centre
- Open-label
- Crossover
- Single-centre
Primary result
Body weight change · 1 week
Difference
1.1 kg
95% CI 0.2–2.0
P = 0.021
UPFvs Non-UPF
difference 1.1 kg (95% CI 0.2–2.0); P = 0.021
As reported in the abstract
Secondary outcomes
| Outcome | Difference (kcal per day) (CI) | P value | |
|---|---|---|---|
| Average daily energy intake | 813.5 (342.4–1284.7) | P = 0.0041 | |
| −1000010002000Difference, kcal per day (linear scale) |
| Outcome | P value |
|---|---|
| Chews per calorieSignificantly lower with UPF | P = 0.016 |
Original publication
Ultra‐processed foods cause weight gain and increased energy intake associated with reduced chewing frequency: A randomized, open‐label, crossover study. Diabetes Obes Metab. Published 12 September 2024. doi:10.
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