Prevalence of complications and co‐morbidities in males and females with obesity: Real‐world insights from claims data analysis
Authors' conclusion
Males with obesity received a diagnosis of cardiovascular risk factors at an earlier age than females, which may have contributed to the higher prevalence of coronary heart disease. Understanding sex-specific variations in co-morbidities across ages can support early screening and diagnosis of risk clusters for optimal obesity management.
Study context
- Population
- Adults (age ≥ 18 years) with a diagnosis of obesity and continuous insurance coverage 2018–2020, Merative MarketScan Research Databaseseligible sample 6.9 million
- Participants
- 2,028,273 adults
- Exposure
- Females vs males with obesity
- Outcome
- Prevalence of co-morbidities in males and females across age groups
Methodological detailsUS commercial and Medicare claims data, age-adjusted odds ratios (ORs)
- US commercial and Medicare claims data
- Age-adjusted ORs
Main finding
As reported in the abstract
Most prevalent co-morbidities
Hypertension, males vs females
62.8% vs. 52.2%
Dyslipidaemia, males vs females
63.3% vs. 50.3%
Depression and/or anxiety (D/A), males vs females
29.7% vs. 48.5%
Observational data: associations, not effects.
Further findings
Sex distribution
| Outcome | Estimate | P value |
|---|---|---|
| Co-morbidities by sex, age-adjustedHigher odds in females | OR, osteoarthritis 1.33 | P < 0.0001 |
| Co-morbidities by sex, age-adjustedHigher odds in females | OR, depression 2.22 | P < 0.0001 |
| Co-morbidities by sex, age-adjustedHigher odds in females | OR, osteoporosis 7.10 | P < 0.0001 |
Age patterns
- Diagnosis of hypertension and dyslipidaemia earlier in males than females
- 6-8 years
- D/A prevalence high in younger age group, steadily decreased with age in both sexes; hypertension and dyslipidaemia increased with age
Original publication
Prevalence of complications and co‐morbidities in males and females with obesity: Real‐world insights from claims data analysis. Diabetes Obes Metab. Published 11 September 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →