Associations between obesity, a composite risk score for probable long COVID, and sleep problems in SARS-CoV-2 vaccinated individuals
Authors' conclusion
Even post-vaccination, individuals with obesity may encounter a heightened risk of experiencing prolonged COVID-19 symptoms. However, confirming our observations necessitates comprehensive studies incorporating rigorous COVID infection testing, such as antibody assays - unavailable in our anonymous survey. Additionally, it is noteworthy that the correlation between probable long COVID and sleep disturbances appears to be independent of BMI.
Study context
- Population
- Adults aged 18 to 89 who received two SARS-CoV-2 mRNA vaccinations
- Participants
- 5,919 adults
- Exposure
- Obesity and overweight vs normal weight
- Outcome
- Probable long COVID: PASC score of 12 or higher
Methodological detailssurvey, anonymous
- Survey
- Anonymous
Main finding
As reported in the abstract
PASC score ≥12 (probable long COVID)
Each group vs normal weightEstimate (95% CI)
Obesity
adjusted OR 1.55(1.05–2.28)
Overweight
OR 0.92(0.63–1.33)
Observational data: associations, not effects.
Further findings
Heightened sleep burden (e.g. obstructive sleep apnea or insomnia)
- Both obesity and probable long COVID associated with increased odds of heightened sleep burden
- P < 0.001
- No significant interaction between BMI and probable long COVID status
Original publication
Associations between obesity, a composite risk score for probable long COVID, and sleep problems in SARS-CoV-2 vaccinated individuals. Int J Obes (Lond). Published 7 June 2024. doi:10.
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