The circulating and central endocannabinoid system in obesity and weight loss
Authors' conclusion
Available evidence does not univocally support that circulating endocannabinoids are upregulated in individuals with obesity, which may be explained by variability across studies in several potential confounding factors (e.g. age and sex) as well as heterogeneity within the obesity population (e.g. BMI only vs. intra-abdominal adiposity).
Study context
- Population
- Human studies of central and circulating endocannabinoid levels in obesity and after bariatric surgery and other weight loss strategies56 human studies
- Outcome
- Endocannabinoid system in obesity and weight loss
Methodological detailsPubMed, Embase and Web of Science searched
- PubMed, Embase and Web of Science searched
Pooled result
As reported in the abstract
Negative correlation between BMI and brain CB1 receptor availability
2 studies
Pharmacological weight management: no effect on AEA concentrations
1 study
Changes in circulating endocannabinoids after bariatric surgery: conflicting results
6 studies
Original publication
The circulating and central endocannabinoid system in obesity and weight loss. Int J Obes (Lond). Published 4 June 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →