Obesity rather than diabetes impacted severe Covid-19 on reunion island: A retrospective cohort study from a frontline hospital, 2020–2021
Authors' conclusion
This study reveals an unexpected prominence of obesity on T2DM (without precision) in the development of severe Covid-19. Despite a high prevalence of T2DM, this finding may partially explain why Covid-19 did not have an even greater impact on the island. Further studies should also consider the treatment of diabetes, diabetic complications, glycemic imbalance or stratify by the novel subgroups of T2DM to better understand the link between T2DM and severe Covid-19 in the Reunionese population.
Study context
- Population
- Patients hospitalized for Covid-19 on Reunion Island, March 11th, 2020 to August 4th, 2021; median age 56 years [42–68], 54% men
- Participants
- 681 patients
- Exposure
- Obesity, diabetes, or both vs neither
- Outcome
- Severe Covid-19 (WHO definition, including deaths)
Methodological detailsobservational, multilevel logistic model with variant circulation period as random effect
- Observational
- Multilevel logistic model with variant circulation period as random effect
Main finding
As reported in the abstract
Severe Covid-19
Adjusted odds ratio (95% CI)P value
Obese
2.64(1.46–4.78)
Diabetic and obese
2.96(1.47–5.93)
Diabeticadjusted for individual characteristics and variant circulation period
1.24(0.68–2.24)
P = 0.471Observational data: associations, not effects.
Original publication
Obesity rather than diabetes impacted severe Covid-19 on reunion island: A retrospective cohort study from a frontline hospital, 2020–2021. Diabetes Metab. Published 9 December 2024. doi:10.
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